Phi-X
TR

Instruments for the lab and the clinic

Much of our work ends up as a physical instrument. Some examples:

  • Culture monitoring. A low-cost top-stage incubator with integrated lens-free holographic imaging lets cells be watched continuously without moving them out of their environment.
  • Spectrometers. Speckle-enhanced prism spectrometers combine a simple prism with a scattering element to reach high resolution and dynamic range in a compact package (US Patent 11,231,322).
  • Fabrication with holographic feedback. Maskless lithography that checks the part being made with holography during fabrication, for producing optical elements.
  • Microscope autofocus (WO 2024/208601), and real-time holographic tracking and control of microrobots.

Undergraduate teams build working devices too; see the student projects.

Key publications

  1. An integrated top-stage incubator and lens-free holographic imaging system for culture monitoring applications

    Zeynep Ozbilgin, Sevdenur Aksit, M. Fatih Toy

    In SPIE Photonics Europe 2022 Unconventional Optical Imaging III, Proc. SPIE 12136, 121360V, Strasbourg, 2022Conference paper

    DOIPDFLink
    Cite
    @inproceedings{ozbilgin2022integrated,
  title={An integrated top-stage incubator and lens-free holographic imaging system for culture monitoring applications},
  author={Ozbilgin, Zeynep and Aksit, Sevdenur and Toy, M Fatih},
  booktitle={Unconventional Optical Imaging III},
  volume={12136},
  pages={237--243},
  year={2022},
  organization={SPIE}
}

  2. Low-Cost top stage incubator for live cell imaging applications

    Zeynep Ozbilgin, Sevdenur Aksit, M. Fatih Toy

    In 2021 Medical Technologies Congress (TIPTEKNO), Antalya, 2021Conference paper

    DOIPDFLink
    Cite
    @inproceedings{ozbilgin2021low,
  title={Low-cost top stage incubator for live cell imaging applications},
  author={{\"O}zbilgin, Zeynep and Toy, M Fatih and Ak{\c{s}}it, Sevdenur},
  booktitle={2021 Medical Technologies Congress (TIPTEKNO)},
  pages={1--4},
  year={2021},
  organization={IEEE}
}

  3. High resolution prism spectrometer comprising a diffuser film

    Onur Ferhanoglu, M. Fatih Toy, S. Kaan Cetindag, Fehmi Civitci

    US Patent, 2022Patent

    PDFLink
    Cite
    @misc{ferhanoglu2022high,
  title={High resolution prism spectrometer comprising a diffuser film},
  author={Ferhanoglu, Onur and Toy, Muhammed Fatih and Cetindag, Sakir Kaan and Civitci, Fehmi},
  year={2022},
  month=jan # "~25",
  publisher={Google Patents},
  note={US Patent 11,231,322}
}

  4. Scattering metal waveguide based speckle-enhanced prism spectrometry

    S. Kaan Cetindag, M. Fatih Toy, Onur Ferhanoglu, Fehmi Civitci

    Journal of Lightwave Technology, 38 (7), 2020Journal article

    DOIPDF
    Cite
    @article{ccetindaug2020scattering,
  title={Scattering metal waveguide based speckle-enhanced prism spectrometry},
  author={{\c{C}}etinda{\u{g}}, Sakir Kaan and Toy, Muhammed Fatih and Ferhano{\u{g}}lu, Onur and Civitci, Fehmi},
  journal={Journal of Lightwave Technology},
  volume={38},
  number={7},
  pages={2022--2027},
  year={2020},
  publisher={IEEE}
}

  5. Maskless lithography with holographic feedback for the fabrication of optical elements

    Tolga Gurcan, M. Fatih Toy

    In SPIE Photonics Europe 2022 3D Printed Optics and Additive Photonic Manufacturing III, Proc. SPIE 12135, 1213508, Strasbourg, 2022Conference paper

    DOIPDFLink
    Cite
    @inproceedings{gurcan2022maskless,
  title={Maskless lithography with holographic feedback for the fabrication of optical elements},
  author={G{\"u}rcan, Tolga and Toy, Muhammed Fatih},
  booktitle={3D Printed Optics and Additive Photonic Manufacturing III},
  volume={12135},
  pages={56--60},
  year={2022},
  organization={SPIE}
}

  7. Microscope with autofocus system

    Sebastien Equis, Nicolas Pavillon, Camille Crunelle, Philippe Paccaud, M. Fatih Toy

    WIPO (PCT), 2024Patent

    PDFLink

  8. Real-time holographic tracking and control of microrobots

    Ayoung Hong, Burak Zeydan, Samuel Charreyron, Olgac Ergeneman, Salvador Pane, M. Fatih Toy, Andrew J. Petruska, Bradley J. Nelson

    IEEE Robotics and Automation Letters, 2 (1), 2016Journal article

    DOIPDF
    Cite
    @article{hong2016real,
  title={Real-time holographic tracking and control of microrobots},
  author={Hong, Ayoung and Zeydan, Burak and Charreyron, Samuel and Ergeneman, Olga{\c{c}} and Pane, Salvador and Toy, M Fatih and Petruska, Andrew J and Nelson, Bradley J},
  journal={IEEE Robotics and Automation Letters},
  volume={2},
  number={1},
  pages={143--148},
  year={2016},
  publisher={IEEE}
}